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Filtered Search Results
Medchemexpress LLC Glyoxal | 107-22-2 | MFCD00006957 | 58.04 | C2H2O2 | 25mL
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Glyoxal is a cytotoxic -oxoaldehyde Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs) Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis cataract Alzheimer s disease) and the formation of calcium oxalate kidney stones[1][2]
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Ambeed AMBEED
5000949976 25-DI-TERT-BUTYLBENZOIC A 50MG
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Medchemexpress LLC BSJ-03-123 | 2361493-16-3 | 99.19% | 937.01 | 10 MG
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BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK, functioning as a potent and novel CDK6-selective small-molecule degrader. It causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
- Potent and novel CDK6-selective small-molecule degrader
- Induces G1 cell-cycle arrest in AML cell lines
- Causes anti-proliferative effect in CDK6-dependent AML cell lines
- Does not significantly increase apoptosis
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eMolecules EMOLECULES INC
5000841112 POTASSIUM DI-TERT-BUTYLPHO 5G
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eMolecules 56-81-5 | Glycerin USP grade | Oakwood Chemicals | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 100g | 480152360
Glycerin USP grade | Oakwood Chemicals | 56-81-5 | MFCD00004722 | 92.094 | C3H8O3 | 99.000 | OCC(O)CO | 100g | 480152360
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Apexbio Technology LLC Rhodamine 123 (chloride) 62669-70-9 10mg
Rhodamine 123 chloride (CAS 62669-70-9) is a cationic fluorescent dye targeting the mitochondrial membrane potential ( m) It is designed to selectively accumulate within the mitochondrial matrix by crossing the plasma membrane thus enabling detection of mitochondrial function and membrane integrity Rhodamine 123 chloride exerts its biological activity primarily by responding to changes in mitochondrial membrane potential producing yellow-green fluorescence upon accumulation in live-cell mitochondria In cell-based studies its fluorescence intensity directly reflects m but no specific IC50 or EC50 value or experimental cell line is reported Based on these properties Rhodamine 123 chloride holds research potential in measuring mitochondrial function assessing apoptosis evaluating ATP production and monitoring P-glycoprotein-mediated efflux in fluorescence microscopy and flow cytometry applications
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Medchemexpress LLC Liothyronine-13C6-1 | 1213431-76-5 | 98.1% | C913C6H12I3NO4 | 100 UG
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Liothyronine-13C6-1 is a 13C-labeled Liothyronine, a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Fostemsavir Tris | 864953-39-9 | C29H37N8O11P | 10 MM/ML
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Fostemsavir Tris (BMS-663068 (Tris)) is a phosphonooxymethyl proagent of BMS-626529. This novel attachment inhibitor targets HIV-1 gp120, preventing its binding to CD4+ T cells. It demonstrates significant antiviral activity in subjects with susceptible viruses, making it a valuable compound for research applications.
- Targets HIV-1 gp120
- Prevents binding to CD4+ T cells
- Exhibits good antiviral activity
- Intended for research use
- Available as a solution in DMSO
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Medchemexpress LLC YB-0158 (Wnt pathway inhibitor 2) | 1144043-83-3 | 99.8% | 703.59 | 1 MG
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YB-0158 is a reverse-turn peptidomimetic and a potent colorectal cancer stem cell (CSC) targeting agent. It disrupts Sam68-Src interactions and induces apoptosis in CRC cells, demonstrating anti-cancer activities.
- Disrupts Sam68-Src interactions.
- Induces apoptosis in CRC cells.
- Potent colorectal cancer stem cell (CSC) targeting agent.
- Shows anti-cancer activities.
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Teknova 10% Tween-20 Solution, 250mL, Sterile. 2 Pack.
Tween Solution is a nonionic detergent used for protein extraction and isolation of nuclei from mammalian cell lines. It is soluble in water and is widely used in biochemical applications such as solubilizing proteins, isolating nuclei from cells, and emulsifying and dispersing substances in medicinal and food products.
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Medchemexpress LLC YB-0158 | 1144043-83-3 | 99.8% | 703.59 | 1 ML
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YB-0158 is a reverse-turn peptidomimetic and a potent targeting agent for colorectal cancer stem cells. It works by disrupting Sam68-Src interactions and inducing apoptosis in colorectal cancer cells, demonstrating anti-cancer activities.
- Significantly increases apoptosis in colorectal cancer cells, as shown by activated Caspase-3/7 detection assays.
- Decreases CBP recruitment at the promoter of Wnt/beta-Catenin target genes LGR5 and MYC in HT29 cells.
- Displays an EC50 (1.64 μM) in cultured MC38 cells.
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Medchemexpress LLC Rhodamine 123 | 62669-70-9 | 99.5% | 25 MG
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Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence. At certain concentrations, rhodamine dyes have low toxicity to cells, making them commonly used to detect mitochondria in animal cells, plant cells, and microorganisms.
- Fluorescent dye
- Specifically recognizes mitochondrial membrane potentials
- Attaches to mitochondria and produces bright fluorescence
- Low toxicity to cells at certain concentrations
- Used to detect mitochondria in animal cells, plant cells, and microorganisms
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eMolecules 629-30-1 | Ambeed | 17-Heptanediol | 5g | 525207569 | A415270 | MFCD00002987 | 132.203 | C7H16O2
Ambeed | 17-Heptanediol | 5g | 525207569 | A415270 | 629-30-1 | MFCD00002987 | 132.203 | C7H16O2
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Medchemexpress LLC Dnsah-13C6 | MFCD00129753 | 100.0% | 248.10 g/mol | C13C6H6N4O6 | 1 MG
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DNSAH-13C6 is a carbon-13 (13C6) stable isotope-labeled analogue of DNSAH supplied as a solid for use as a tracer or internal standard in quantitative analyses, including NMR, GC-MS, and LC-MS. For research use only.
- Stable isotope-labeled tracer for metabolic flux and quantitative analysis.
- Chemical purity 99.98%.
- Isotopic labeling: carbon-13 (13C6).
- Molecular formula C13C6H6N4O6; molecular weight 248.10 g/mol.
- Light yellow to yellow solid form.
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Intended for use as a tracer or internal standard in NMR, GC-MS, and LC-MS.
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TARGETMOL CHEMICALS INC MG 149 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM similar potentcy for MOF(IC50= 47 uM). purity: 99%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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